Visual Evoked Potentials in Operated Primary Congenital Glaucoma: A Cross-Sectional Comparative Study

Area of Science:

• Ophthalmology
• Pediatric Ophthalmology
• Neuro-ophthalmology

Background:

• Primary congenital glaucoma (PCG) is a severe pediatric eye condition requiring surgical intervention.
• Assessing visual pathway function post-surgery is crucial for understanding long-term outcomes.
• Visual evoked potential (VEP) testing can evaluate the integrity of the visual pathway.

Purpose of the Study:

• To evaluate visual evoked potential (VEP) parameters in surgically managed primary congenital glaucoma (PCG) eyes.
• To compare VEP parameters between operated PCG eyes and age-matched healthy children's eyes.

Main Methods:

• A cross-sectional comparative study included 26 children with operated PCG and 22 age-similar controls.
• Standard ophthalmic examination and electrophysiological testing (single flash VEP) were performed.
• VEP parameters analyzed included P2 implicit time and N1-P1, N2-P2 amplitudes.

Main Results:

• No statistically significant differences were found in VEP parameters (P2 implicit time, N1-P1, N2-P2 amplitudes) between operated PCG eyes and control eyes.
• The mean age of study participants and controls was comparable.
• No significant correlation was observed between clinical characteristics and VEP parameters in PCG eyes.

Conclusions:

• Surgically controlled primary congenital glaucoma (PCG) eyes demonstrate visual evoked potential (VEP) parameters similar to those of healthy children.
• These findings suggest that successful surgical management of PCG results in normal visual pathway function as assessed by VEP.