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How many children with large clear cornea do not have glaucoma?
Nader Bayoumi1, Eman Nabil Elsayed1, Ahmed Saber2
1Ophthalmology Department, Alexandria University faculty of Medicine, Alexandria, Egypt.
European Journal of Ophthalmology
|April 6, 2023
Summary
A significant portion of children with large clear corneas do not have glaucoma. Many of these cases are associated with axial myopia, not congenital megalocornea.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Genetics
Background:
- Megalocornea, defined as a large clear cornea, can be associated with glaucoma.
- Differentiating glaucoma from other causes of large corneas in children is crucial for appropriate management.
Purpose of the Study:
- To determine the incidence and clinical characteristics of large clear corneas in children.
- To identify the prevalence of glaucoma in children presenting with large clear corneas.
Main Methods:
- Retrospective chart review of pediatric patients with large clear corneas (horizontal white-to-white corneal diameter > 12 mm).
- Glaucoma diagnosis based on Childhood Glaucoma Research Network (CGRN) criteria.
- Axial length measurements used to exclude congenital high myopia.
Main Results:
- Out of 120 eyes from 91 children, 44 eyes (36.7%) from 24 children did not have glaucoma.
- Of the eyes without glaucoma, 30 were classified as myopia and 14 as congenital megalocornea.
- Glaucoma was diagnosed in 76 eyes (63.3%) from 67 children.
Conclusions:
- Over one-third of pediatric eyes presenting with large clear corneas do not have glaucoma.
- Axial myopia is a common finding in children with large clear corneas not associated with glaucoma.
- This highlights the importance of thorough ophthalmological evaluation to differentiate glaucoma from other conditions causing large corneas.
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