Intracranial Volume Not Correlated With Severity in Trigonocephaly.

Area of Science:

• Pediatric Neurosurgery
• Craniofacial Surgery
• Medical Imaging

Background:

• Trigonocephaly, a skull deformity, can vary in severity and potentially impact intracranial volume (ICV) and intracranial pressure (ICP).
• Understanding the relationship between trigonocephaly severity and ICV is crucial for patient management.

Purpose of the Study:

• To measure ICV in patients with trigonocephaly.
• To compare measured ICV with normative data.
• To correlate ICV with the severity of skull deformity using the Utrecht Cranial Shape Quantifier (UCSQ).

Main Methods:

• Retrospective study of 19 preoperative patients with nonsyndromic trigonocephaly (age ≤12 months).
• Intracranial volume (ICV) measured via manual segmentation on computed tomography (CT) scans.
• Utrecht Cranial Shape Quantifier (UCSQ) used to assess skull deformity severity.

Main Results:

• Mean measured ICV was within normal ranges compared to Lichtenberg normative growth curves.
• Thirteen of 19 patients had ICV within ±2 SD of normative data.
• Correlation between trigonocephaly severity (UCSQ) and ICV was negligible (r = -0.11).

Conclusions:

• Measured ICV in trigonocephaly patients falls within normal ranges, irrespective of deformity severity.
• No significant correlation exists between the severity of trigonocephaly and intracranial volume.
• No papilledema was reported, suggesting no consistent elevation of intracranial pressure in this cohort.