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Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules
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Kv2 channel-AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking.

Emily E Maverick1,2, Ashley N Leek1,2, Michael M Tamkun1,2,3

  • 1Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

Journal of Cell Science
|June 17, 2021
PubMed
Summary

The AMIGO proteins interact with Kv2 channels, influencing their electrical activity and cellular localization. This interaction fine-tunes both electrical and non-electrical cell functions.

Keywords:
AMIGOER–PM junctionElectrophysiologyKv2Membrane localizationTrafficking

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