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Published on: November 5, 2021
Portal thrombosis in a patient with SARS-CoV-2 infection
David Ortiz López1, Alicia Puente Fernández2, Isabel Ramos Gómez2
1Cirugía General y del Aparato Digestivo, Hospital Universitario de Gran Canaria Dr. Negrín, España.
Abstract:
The digestive manifestations of a SARS-CoV-2 infection are varied and nonspecific. The appearance of portal thrombosis in these patients is very rare. Facing a patient with a diagnosis of acute portal thrombosis, we must rule out that the trigger is an intra-abdominal infectious process. We present the case of a patient diagnosed with severe pneumonia due to SARS-CoV-2 infection with elevated D-Dimer and a concomitant diagnosis of portal thrombosis not attributed to other causes.
Insights
Severe COVID-19 can rarely cause portal vein thrombosis, a serious condition affecting blood flow in the liver. This case highlights the need to consider SARS-CoV-2 as a potential cause for this rare complication.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Vascular Medicine
Background:
- Digestive symptoms are common but nonspecific in SARS-CoV-2 infections.
- Portal vein thrombosis is an exceptionally rare manifestation of COVID-19.
Observation:
- A patient with severe SARS-CoV-2 pneumonia presented with elevated D-Dimer levels.
- The patient was diagnosed with acute portal thrombosis without other identifiable causes.
Findings:
- This case suggests a potential link between SARS-CoV-2 infection and the development of portal vein thrombosis.
- Elevated D-Dimer levels in COVID-19 patients may indicate an increased risk for thrombotic events.
Implications:
- Clinicians should consider SARS-CoV-2 infection in the differential diagnosis of unexplained portal thrombosis.
- Further research is warranted to understand the pathophysiology and incidence of portal vein thrombosis in COVID-19 patients.
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