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[Clinico-therapeutic and microbiological research on the preparation Monaspor in patients with active pyelonephritis]
Abstract:
The urinary antiseptic efficacy of cefsulodin (Monaspor--Ciba) was studied in 22 patients with active pyelonephritis. The results were considered very good in 81.8% of the patients with urologic infections caused by P. aeruginosa, P. mirabilis and E. Coli. The drug was well tolerated. The microbiological studies in vitro of the urinary antiseptic efficacy of Monaspor on 575 bacterial strains isolated from patients with active pyelonephritis showed that the antibiotic was most active against Pseudomonas sp., beta-streptococcus, Staph. aureus, P. mirabilis.
Insights
Cefsulodin demonstrated excellent urinary antiseptic efficacy in patients with pyelonephritis, particularly for infections caused by Pseudomonas aeruginosa. This antibiotic showed high effectiveness and good tolerability in clinical and in vitro studies.
Area of Science:
- Pharmacology
- Urology
- Microbiology