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Biomarkers in Rheumatoid Arthritis
1Rheumatology, University of Texas at Austin, Dell Medical School, Austin, USA.
Cureus
|June 18, 2021
Summary
Biomarkers are crucial for rheumatoid arthritis (RA) diagnosis and management. This review covers current clinical biomarkers and promising investigational ones for RA.
Area of Science:
- Rheumatology
- Immunology
- Clinical Diagnostics
Background:
- Rheumatoid arthritis (RA) diagnosis and management require effective biomarkers.
- Identifying reliable biomarkers aids in early detection and personalized treatment strategies for RA patients.
Purpose of the Study:
- To review biomarkers currently used in routine clinical practice for rheumatoid arthritis (RA).
- To discuss investigational biomarkers with potential for future clinical application in RA.
- To highlight unresolved clinical questions regarding biomarker utility in RA management.
Main Methods:
- Literature review of scientific publications on rheumatoid arthritis biomarkers.
- Analysis of biomarkers for clinical utility, diagnostic accuracy, and prognostic value.
- Synthesis of information on established and emerging biomarkers for RA.
Main Results:
- Several biomarkers are established for routine RA diagnosis and monitoring.
- A range of investigational biomarkers show promise for enhanced RA management.
- Significant clinical questions remain regarding the optimal application of certain biomarkers in RA.
Conclusions:
- Biomarker utilization is advancing the field of rheumatoid arthritis care.
- Continued research into novel biomarkers is essential for improving RA patient outcomes.
- Addressing outstanding clinical questions will optimize the use of biomarkers in RA.
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