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Updated: Dec 14, 2025

Cardiac Magnetic Resonance Imaging at 7 Tesla
Published on: January 6, 2019
Complete Heart Block in Systemic Sclerosis with Characterization on Cardiac MRI
Paul Guzik1, Audrey Han1, Samantha C Shapiro1
1UNIVERSITY OF TEXAS AT AUSTIN DELL MEDICAL SCHOOL, AUSTIN, TEXAS.
Insights
Systemic sclerosis can affect the heart, rarely causing third-degree atrioventricular block. Cardiac magnetic resonance imaging (CMR) was used for diagnosis and prognosis in this rare systemic sclerosis case.
Area of Science:
- Cardiology
- Rheumatology
- Medical Imaging
Background:
- Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis affecting multiple organs, including the heart.
- Cardiac involvement in SSc significantly increases morbidity and mortality, with potential impact on all cardiac structures.
- While cardiac manifestations are known, involvement of the conduction system is less common.
Observation:
- A rare case of SSc presenting with third-degree atrioventricular block (AVB) is described.
- Cardiac magnetic resonance imaging (CMR) was utilized as a key diagnostic and prognostic tool in this patient.
- This represents the first reported use of CMR for diagnosing AVB in the context of SSc.
Findings:
- CMR successfully identified the extent of cardiac involvement and provided prognostic information in a patient with SSc-induced AVB.
- The study highlights the potential of CMR in evaluating conduction system abnormalities in SSc.
Implications:
- The findings suggest CMR may aid in earlier diagnosis and risk stratification for cardiac complications in SSc.
- Further research is needed to determine if CMR-guided management leads to improved patient outcomes or timely transplant referral.
- This case underscores the importance of considering cardiac involvement, including conduction abnormalities, in patients with systemic sclerosis.
Abstract:
Cardiac involvement of infiltrative disease, such as systemic sclerosis, carries significant morbidity and mortality. All parts of the heart may be affected, although the conduction system is less commonly involved. We report a rare case of systemic sclerosis causing third-degree atrioventricular block and the first known reported case to use cardiac magnetic resonance imaging (CMR) as a diagnostic and prognostic instrument. It is not known whether using cardiac CMR in systemic sclerosis with cardiac involvement could lead to earlier intervention with escalation of medical therapy or earlier referral for transplant evaluation.
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