Related Experiment Video
Updated: Nov 1, 2025

09:36
Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
Published on: December 22, 2023
1.4K
Arrhythmogenic right ventricular cardiomyopathy characterized by recurrent syncope during exercise: A case report
Hao-Yu Wu1, Yi-Wei Cao2, Tian-Jiao Gao3
1Department of Cardiology, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
World Journal of Clinical Cases
|June 18, 2021
Summary
Arrhythmogenic right ventricular cardiomyopathy (ARVC) can cause syncope during exercise. Combined endocardial and epicardial catheter ablation successfully treated a patient with ARVC, preventing adverse events.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare condition.
- It involves fibrofatty tissue replacing right ventricular myocardium.
- ARVC can lead to syncope, heart failure, and sudden cardiac death, especially during exercise.
Observation:
- A 43-year-old man presented with recurrent syncope during exercise.
- Diagnostic workup revealed ventricular tachycardia, RV abnormalities on MRI, and inducible VT on electrophysiology study.
- The patient was diagnosed with ARVC.
Findings:
- Combined endocardial and epicardial catheter ablation was performed.
- The procedure successfully treated the patient's ventricular tachycardia.
- The patient experienced a satisfactory follow-up outcome.
Implications:
- Clinicians must maintain a high awareness of ARVC.
- Multimodality imaging is essential for accurate diagnosis.
- Combined epicardial and endocardial ablation is an effective therapeutic strategy for ARVC.

