Subzero balance - simple modified ultrafiltration (SBUF-SMUF) technique for pediatric cardiopulmonary bypass

Joel Bierer1, Mark Henderson2, Roger Stanzel2

  • 1Division of Cardiac Surgery, Department of Surgery, Dalhousie University, Halifax, Canada.

Perfusion
|June 18, 2021
PubMed

Insights

Pediatric cardiac surgery using cardiopulmonary bypass (CPB) can cause complications. A new ultrafiltration method, Subzero Balance Simple Modified Ultrafiltration (SBUF-SMUF), aims to improve patient recovery after surgery.

Area of Science:

  • Cardiovascular Surgery
  • Pediatric Critical Care
  • Biomedical Engineering

Background:

  • Cardiopulmonary bypass (CPB) in pediatric cardiac surgery is linked to hemodilution, coagulopathy, and systemic inflammation.
  • Intra-operative ultrafiltration is a standard method to mitigate CPB-associated adverse effects.

Purpose of the Study:

  • To introduce and describe a novel ultrafiltration technique, Subzero Balance Simple Modified Ultrafiltration (SBUF-SMUF).
  • To evaluate the potential of SBUF-SMUF to enhance recovery in pediatric patients following cardiac surgery and CPB.

Main Methods:

  • The study describes the SBUF-SMUF technique, combining continuous and non-continuous ultrafiltration modalities.
  • Application of SBUF-SMUF during intra-operative procedures in pediatric cardiac surgery.

Main Results:

  • The SBUF-SMUF technique aims to reduce adverse effects associated with CPB.
  • Enhanced recovery is the anticipated outcome for pediatric patients undergoing cardiac surgery.

Conclusions:

  • SBUF-SMUF represents a novel approach to ultrafiltration in pediatric cardiac surgery.
  • This technique holds promise for improving patient outcomes and recovery post-CPB.

Related Concept Videos

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
28
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
255
Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
569
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
44