Related Experiment Video
Updated: Nov 1, 2025

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
Published on: June 5, 2010
[Diagnostics and treatment of statin-associated muscle symptoms]
Ursula Kassner, Stefanie Grunwald, Dominik Spira
1Lipidambulanz, Klinik für Endokrinologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. elisabeth.steinhagen-thiessen@gmx.de.
Abstract:
Statins are among the most frequently prescribed drugs in Germany. Their benefits in lowering cardiovascular risk are beyond dispute. Nevertheless, many patients complain of side effects from statin therapy, including statin-associated muscle symptoms (SAMS) in particular. Despite their relative frequency, it is difficult to objectively diagnose them, as the time until appearance of first symptoms, the nature of the complaints and the severity of muscle problems vary widely. This narrative review summarizes the causes of SAMS as well as new possibilities regarding their diagnosis and therapy.
Related Concept Videos
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Atherosclerosis III: Management
Skeletal Muscle Relaxants: Adverse Effects
Unlike...
Myocarditis III: Medical Management

