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Benzodiazepines and Sleep Architecture: A Systematic Review

Felipe Maraucci Ribeiro de Mendonça1, Giulia Paulo Rossi Ribeiro de Mendonça2, Laura Costa Souza1

  • 1Health Secretariat of São Bernardo do Campo, São Bernardo do Campo, SP, Brazil.

CNS & Neurological Disorders Drug Targets
|June 19, 2021
PubMed
Summary

Benzodiazepines (BZDs) alter sleep architecture by increasing stage 2 Non-Rapid Eye Movement (NREM) sleep while decreasing deep NREM sleep and Rapid Eye Movement (REM) sleep. Careful prescription and monitoring are advised due to potential side effects.

Keywords:
Benzodiazepinessleepsleep REMsleep architecturesleep slow-wavesleep stages

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