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Knowledge Domain and Emerging Trends in Ferroptosis Research: A Bibliometric and Knowledge-Map Analysis
Jie Zhang1,2, Luxia Song1,2, Liyan Xu3
1Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Frontiers in Oncology
|June 21, 2021
Summary
This bibliometric analysis maps ferroptosis research, identifying key contributors, trends, and emerging topics. It highlights the growing knowledge base and potential future research directions in this critical cell death pathway.
Area of Science:
- Biomedical Sciences
- Molecular Biology
- Cell Death Research
Background:
- Ferroptosis is a crucial form of regulated cell death with implications for various diseases.
- Understanding the landscape of ferroptosis research is essential for identifying knowledge gaps and future directions.
- Bibliometric analysis provides a quantitative overview of scientific output and collaboration.
Purpose of the Study:
- To map the intellectual structure and evolution of ferroptosis research.
- To identify key authors, institutions, countries, and journals in the field.
- To detect current research hotspots and emerging trends in ferroptosis.
Main Methods:
- Bibliometric and knowledge-map analysis of 1,267 ferroptosis-related publications.
- Data sourced from the Web of Science Core Collection up to November 1, 2020.
- Scientometric software CiteSpace and VOSviewer were utilized for analysis.
Main Results:
- Rapidly increasing publication output, with the United States and China as leading countries.
- Key research areas include regulatory mechanisms, nervous system injury, cancer, and lipid peroxidation.
- Current hotspots include nanoparticles, cancer therapy, and iron metabolism, with Nrf2 showing potential significance.
Conclusions:
- This bibliometric study provides a comprehensive overview of ferroptosis research.
- Identified trends and emerging topics offer valuable insights for researchers in the field.
- The findings serve as a helpful reference for scholars focusing on ferroptosis.
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