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Updated: Nov 1, 2025

Automated Hydrophobic Interaction Chromatography Column Selection for Use in Protein Purification
Published on: September 21, 2011
Natural and Artificial Chiral-Based Systems for Separation Applications
Yuan Zhao1,2, Xuecheng Zhu1,2, Wei Jiang1,2
1Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, China.
Abstract:
Chiral separation has attracted much attention for basic research and industrial applications in analytical chemistry. Generally, chiral separations use natural or artificial chiral-based materials as adsorbents. To improve the precision and efficiency of chiral separation, focus has shifted from natural and synthetic adsorbents to binary combinations of materials. This review specifically summarizes the significant advancements made in natural and artificial chiral adsorbents as promising candidates for diverse drug and biomolecule separation applications as well as the remaining drawbacks and challenges for research on chiral separations. The mechanisms of chiral-based recognition and separation and history and development of natural and artificial chiral-based systems are the focus of this review. Future directions in natural and artificial chiral-based systems for practical separations and other applications are also presented.
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