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Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
Using data mining technology to predict medication-taking behaviour in women with breast cancer: A retrospective
Chen-Chen Kuo1,2, Hsiu-Hung Wang2, Li-Ping Tseng3,4
1The Cancer Prevention and Treatment Center, St. Martin De Porres Hospital, Chiayi, Taiwan.
Aims:
Medication-taking behaviours of breast cancer survivors undergoing adjuvant hormone therapy have received considerable attention. This study aimed to determine factors affecting medication-taking behaviours in people with breast cancer using data mining.
Design:
A longitudinal observational retrospective cohort study with a hospital-based survey.
Methods:
A total of 385 subjects were surveyed, analysing existing data from January 2010 to December 2017 in Taiwan. Three data mining approaches-multiple logistic regression, decision tree and artificial neural network-were used to build the prediction models and rank the importance of influencing factors. Accuracy, specificity and sensitivity were used as assessment indicators for the prediction models.
Results:
Multiple logistic regression was the most effective approach, achieving an accuracy of 96.37%, specificity of 96.75% and sensitivity of 96.12%. The duration of adjuvant hormone therapy discontinuation, duration of adjuvant hormone therapy use and age at diagnosis by data mining were the three most critical factors influencing the medication-taking behaviours of people with breast cancer.
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