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Updated: Nov 1, 2025

Multimodal Quantitative Phase Imaging with Digital Holographic Microscopy Accurately Assesses Intestinal Inflammation and Epithelial Wound Healing
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CT-P13 subcutaneous infliximab in gastroenterology and rheumatology

Mai Ahmed1, Giulia Bankov2, Dan Casey3

  • 1Department of Rheumatology, Royal Alexandra Hospital, Paisley, UK.

Immunotherapy
|June 23, 2021
PubMed

The drug infliximab has been a key milestone in the treatment of inflammatory conditions such as Crohn's disease, ulcerative colitis, rheumatoid arthritis and the seronegative spondyloarthritides. Biosimilar drugs followed the originator, further improving access and diversity of therapy choice. Subcutaneous infliximab (CT-P13) holds potential for greater patient flexibility by self administration, reducing travel and hospital attendance for infusion, particularly relevant at a time of pandemic. We highlight the pharmacodynamic and pharmacokinetic basis of the subcutaneous device, clinical trials in rheumatology and gastroenterology and consider the safety and cost implications. Real-world switching data is required to confirm the efficacy data from clinical trials given the reduction in dosing flexibility compared with intravenous therapy.

Keywords:
CT-P13inflammatory bowel diseaseinfliximabrheumatoid arthritissubcutaneous

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