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Updated: Nov 1, 2025

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
[Acute Colonic Pseudo-obstruction Induced by Neuroleptic Malignant Syndrome]
Sung Ju Ryu1, Jong Yoon Lee1, Jong Hoon Lee1
1Division of Gastroenterology, Department of Internal Medicine, Dong-A University Hospital, Busan, Korea.
Abstract:
A colonic pseudo-obstruction is a disorder that causes abdominal distension and abdominal pain similar to a mechanical obstruction, but there are no structural lesions that can obstruct the gastrointestinal tract. This condition can be acute or chronic. An acute colonic pseudo-obstruction, also called Ogilvie's syndrome, is believed to be a condition induced by other causes that are different from a chronic colonic pseudo-obstruction. The pathogenesis involves abnormalities in the autonomic nervous system induced by systemic diseases or medications, and it often improves when the primary causes are treated. On the other hand, a chronic colonic pseudo-obstruction can occur repeatedly without a particular cause. The authors encountered neuroleptic malignant syndrome that caused acute colonic pseudo-obstruction. This paper reports a case with a review of the relevant literature. This is the first case reported in Korea. This case shows that physicians should consider neuroleptic malignant syndrome as a cause of an acute colonic pseudo-obstruction.
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