Related Experiment Video
Updated: Nov 1, 2025
08:50
Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
16.5K
Assessment of Kidney Function After Transcatheter Aortic Valve Replacement
Orit Kliuk-Ben Bassat1, Sapir Sadon2, Svetlana Sirota2
1Department of Nephrology, Tel Aviv Medical Center, Sackler School of Medicine, Tel Aviv University, Israel.
Canadian Journal of Kidney Health and Disease
|June 23, 2021
Summary
Kidney function improvement after transcatheter aortic valve replacement (TAVR) is uncommon and does not impact long-term mortality. Acute kidney injury following TAVR, however, is associated with increased mortality.
Area of Science:
- Cardiology
- Nephrology
- Interventional Cardiology
Background:
- Transcatheter aortic valve replacement (TAVR) carries a risk of acute kidney injury (AKI), but may also improve renal function.
- Understanding kidney function changes post-TAVR is crucial for patient outcomes.
Purpose of the Study:
- To quantify kidney function improvement (KFI) after TAVR.
- To assess the impact of KFI on long-term mortality.
Main Methods:
- Prospective, single-center study of 1321 patients undergoing TAVR.
- Serum creatinine measured pre- and post-procedure (up to 7 days).
- KFI defined by specific creatinine reduction criteria; patients grouped into KFI, AKI, or preserved kidney function (PKF).
Main Results:
- KFI occurred in 5% of patients, often minor.
- AKI incidence was 19.1%.
- Lower eGFR predicted KFI; KFI group had higher STS scores. Mortality was similar between KFI and PKF groups but significantly higher in the AKI group.
Conclusions:
- Kidney function improvement post-TAVR is infrequent and did not reduce mortality in this cohort.
- Limitations include single-center design and varied KFI definitions.
Related Concept Videos
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
108
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
108
01:16Kidney Transplant III: Nursing Management
122
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
122
01:28Kidney Transplant I: Introduction
101
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
101
01:28Cardiac Catheterization I: Pre-Procedure Overview
364
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
364
01:29Acute Kidney Injury III: Clinical Manifestations
359
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
359
01:19Imaging Studies VII: Vascular Imaging
109
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
109