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EPIDEMIOLOGY OF RESPIRATORY PATHOGENS IN CHILDREN WITH ACUTE RESPIRATORY TRACT INFECTION IN UKRAINE DURING 2018-2020

Viktoriia E Khomenko1, Oksana V Iemets1, Oleksandr P Volosovets2

  • 1MEDICAL CENTRE 'EUROLAB', KYIV, UKRAINE; O.O. BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|June 23, 2021
PubMed

Insights

This study identified common respiratory viruses in Ukrainian children, finding Rhinovirus (RV) and Adenovirus (AdV) most prevalent. Understanding pathogen seasonality aids in optimizing treatment and prevention strategies for acute respiratory tract infections (ARTIs).

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Virology

Background:

  • Acute Respiratory Tract Infections (ARTIs) are a significant health concern in children.
  • Identifying causative pathogens is crucial for effective management and prevention.

Purpose of the Study:

  • To determine the prevalence of potential pathogens causing ARTIs in children in Ukraine.
  • To analyze pathogen profiles, clinical characteristics, and seasonality of ARTIs.

Main Methods:

  • Investigated 487 children in Kyiv, Ukraine (2018-2020) for ARTI etiology.
  • Utilized PCR for seven respiratory viruses (RSV, PIV, AdV, MPV, RV, BoV, CoV).
  • Employed chromatographic immunoassay for Influenza A/B and Group A Streptococcus.

Main Results:

  • 82.1% of samples (400/487) tested positive for pathogens.
  • Rhinovirus (RV) was the most common virus (27.1%), followed by Adenovirus (AdV) (13.4%) and Respiratory Syncytial Virus (RSV) (13.2%).
  • Influenza A (IVA) was detected in 10.7% of cases.

Conclusions:

  • Established viral seasonality and clinical features of ARTIs in Ukrainian children.
  • Findings support optimizing therapy and developing preventive measures, including vaccination.
  • Data aids in predicting disease course and improving pediatric ARTI management.
Abstract

Keywords:
Ukraineacute respiratory tract infectionsclinical characteristicspediatricsepidemiology

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