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Related Experiment Video

Updated: Nov 1, 2025

Large Area Substrate-Based Nanofabrication of Controllable and Customizable Gold Nanoparticles Via Capped Dewetting
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Controlling ultrasmall gold nanoparticles with atomic precision.

Nan Xia1,2, Zhikun Wu1,2

  • 1Key Laboratory of Materials Physics, Anhui Key Laboratory of Nanomaterials and Nanostructures, Institute of Solid State Physics, Chinese Academy of Sciences Hefei 230031 P. R. China zkwu@issp.ac.cn.

Chemical Science
|June 24, 2021
PubMed
Summary

Controlling gold nanoparticles with atomic precision is crucial for advancing their applications. This review covers synthesis strategies and methods, focusing on parameters for future atomically precise nanoparticle development.

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Chemistry

Background:

  • Gold nanoparticles are extensively studied due to their stability and unique properties.
  • Controlling gold nanoparticle synthesis with atomic precision has been a long-standing challenge.
  • Recent advances have enabled partial control over ultrasmall gold nanoparticles (nanoclusters).

Purpose of the Study:

  • To review general synthesis strategies for gold nanoparticles.
  • To highlight facile synthesis methods with an emphasis on controlling parameters.
  • To discuss implications for achieving atomic precision in nanoparticle synthesis.

Main Methods:

  • Review of existing literature on gold nanoparticle synthesis.
  • Analysis of well-documented synthesis results and controlling parameters.
  • Focus on methods applicable to ultrasmall gold nanoclusters.

Main Results:

  • Identification of key parameters influencing gold nanoparticle synthesis.
  • Demonstration of partially realized atomic precision in ultrasmall gold nanoclusters.
  • Compilation of synthesis strategies and facile methods.

Conclusions:

  • Achieving atomic precision in gold nanoparticle design and synthesis remains a challenge.
  • Development of extensive atomically precise gold nanoparticle libraries is essential.
  • In-depth understanding of metal nanoparticle chemistry is critical for future advancements.