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Refractory fibromyalgia.

Luis F Vidal1,2, Osvaldo Messina3,4, Tamara Rodríguez5

  • 1Centro de Diagnóstico de Osteoporosis y Enfermedades Reumáticas (CEDOR), Lima, Perú.

Clinical Rheumatology
|June 25, 2021
PubMed
Summary
This summary is machine-generated.

Defining refractory fibromyalgia is complex, as there is no consensus. This article proposes foundational elements for a definition, emphasizing proper diagnosis and treatment response evaluation for better patient management.

Keywords:
Consensus definitionMusculoskeletal painRefractory fibromyalgia

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Area of Science:

  • Rheumatology
  • Clinical Medicine
  • Pharmacology

Background:

  • Fibromyalgia is a chronic pain condition with limited treatment options.
  • Refractory fibromyalgia lacks a clear definition, hindering standardized patient classification and management.
  • Current literature has few references on refractory fibromyalgia, indicating a knowledge gap.

Purpose of the Study:

  • To propose foundational elements for defining treatment-refractory fibromyalgia.
  • To highlight the need for a consensus definition for better patient care.
  • To stimulate discussion on classifying fibromyalgia patients unresponsive to standard treatments.

Main Methods:

  • Literature review on existing definitions and concepts of refractory fibromyalgia.
  • Analysis of diagnostic criteria and differential diagnoses for fibromyalgia.
  • Consideration of factors influencing treatment response, including medication and non-medical elements.

Main Results:

  • No universally accepted definition for refractory fibromyalgia currently exists.
  • A proposed definition should incorporate proper diagnosis, differential diagnosis, and evaluation of treatment response.
  • Key elements include lack of response to a specified number of medications or combination therapy.

Conclusions:

  • A consensus definition for refractory fibromyalgia is crucial for standardizing management strategies.
  • The proposed bases for definition require extensive discussion among experts.
  • Establishing a clear definition will aid in identifying and managing patients with treatment-resistant fibromyalgia.