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Ginseng for Erectile Dysfunction: A Cochrane Systematic Review.

Hye Won Lee1, Myeong Soo Lee2,3, Tae-Hun Kim4

  • 1Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea.

The World Journal of Men'S Health
|June 25, 2021
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Summary

Ginseng shows a small benefit for erectile dysfunction, improving intercourse ability but having minimal impact on overall function or satisfaction. Adverse events were similar to placebo.

Keywords:
Erectile dysfunctionGinsengMeta-analysisPanaxSystematic review

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Area of Science:

  • Integrative Medicine
  • Urology
  • Pharmacology

Background:

  • Erectile dysfunction (ED) is a common condition affecting men's health and quality of life.
  • Ginseng, a traditional herbal medicine, is often explored for its potential therapeutic benefits, including for ED.

Purpose of the Study:

  • To systematically evaluate the efficacy and safety of ginseng as a treatment for erectile dysfunction.
  • To synthesize evidence from randomized and quasi-randomized controlled trials comparing ginseng to placebo or conventional treatments.

Main Methods:

  • A comprehensive literature search was conducted across multiple electronic databases up to January 2021.
  • Nine studies comparing ginseng to placebo were included after independent screening and data extraction.
  • Risk of bias and certainty of evidence (CoE) were assessed using the GRADE approach.

Main Results:

  • Ginseng demonstrated a trivial effect on erectile function (MD 3.52, low CoE) and intercourse satisfaction (MD 1.19, low CoE) compared to placebo.
  • A significant improvement was noted in self-reported ability to have intercourse (RR 2.55, low CoE).
  • Ginseng showed little to no difference in adverse events compared to placebo (RR 1.45, low CoE).

Conclusions:

  • Ginseng may offer a modest benefit for men's self-reported ability to engage in intercourse.
  • The overall effect of ginseng on erectile function and satisfaction appears to be trivial, with low certainty of evidence.
  • Further research may be needed to clarify the role of ginseng in managing erectile dysfunction.