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Updated: Nov 1, 2025

Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Congenital airway anomalies
Patricio Varela1, Claudia Schweiger2
1Program Director Pediatric Airway Unit, Mackenna Children's Hospital, University of Chile, Clínica Las Condes Medical Center. Santiago, Chile.
Abstract:
Congenital airway anomalies (CAA) include a variety of conditions that cause respiratory distress in neonates and infants. These malformations occur at various anatomic levels and manifest in a wide spectrum of airway symptoms, with presentation significantly influenced by the level at which obstruction occurs as well as by the severity of obstruction. The prevalence of congenital airway malformations has been estimated to range between 0.2 and 1 in 10,000 live births. The most frequent CAA are laryngomalacia, bilateral vocal cord paralysis, subglottic stenosis, laryngeal webs, subglottic hemangioma, tracheomalacia, congenital tracheal stenosis, laryngotracheal cleft, and tracheal agenesis.
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