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Related Concept Videos

Vaccinations01:51

Vaccinations

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Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Cross-reactivity00:42

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Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

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The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
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Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Conjugated Proteins02:50

Conjugated Proteins

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Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
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Efficient Transfection of In vitro Transcribed mRNA in Cultured Cells Using Peptide-Poloxamine Nanoparticles
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Efficient Transfection of In vitro Transcribed mRNA in Cultured Cells Using Peptide-Poloxamine Nanoparticles

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[Vaccine against COVID-19].

J J Picazo1

  • 1Juan J. Picazo, Catedrático Emérito de Microbiología Médica. Facultad de Medicina. Universidad Complutense de Madrid, Spain. jpicazo@microb.net.

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|June 28, 2021
PubMed
Summary
This summary is machine-generated.

COVID-19 vaccines represent a significant advancement in combating infectious diseases, built upon recent progress in vaccine technology. This resource provides evidence-based information for healthcare professionals navigating patient queries during the pandemic.

Keywords:
COVID-19SARS-CoV-2effectiveness-safetyvaccinesvariants

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Area of Science:

  • Vaccinology
  • Infectious Disease Epidemiology
  • Public Health

Background:

  • The COVID-19 pandemic caused widespread societal disruption, placing immense pressure on healthcare systems and workers.
  • Healthcare professionals lacked sufficient evidence-based information to address patient concerns regarding COVID-19 vaccines.
  • Rapid advancements in vaccine technology, driven by research in areas like cancer and Alzheimer's disease, facilitated swift vaccine development.

Purpose of the Study:

  • To provide healthcare practitioners with reliable, scientific information on COVID-19 vaccination.
  • To counter misinformation and unverified data circulating during the pandemic.
  • To serve as an accessible, up-to-date resource for addressing patient inquiries about vaccines.

Main Methods:

  • Compilation of scientific evidence and peer-reviewed data on COVID-19 vaccines.
  • Focus on established scientific principles and validated research findings.
  • Online publication format to allow for continuous updates and version control.

Main Results:

  • Vaccines emerged as a critical tool in managing the COVID-19 pandemic.
  • The development of COVID-19 vaccines leveraged recent technological progress in vaccinology.
  • An online platform was established to disseminate timely and accurate vaccination information.

Conclusions:

  • Evidence-based information is crucial for effective public health communication during pandemics.
  • Online, version-controlled publications are effective for disseminating rapidly evolving scientific data.
  • Continued scientific collaboration and transparent data sharing are vital for addressing global health challenges.