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Updated: Oct 31, 2025

Fabrication of Tongue Extracellular Matrix and Reconstitution of Tongue Squamous Cell Carcinoma In Vitro
Published on: June 20, 2018
Tongue squamous cell carcinoma and bilateral kidney metastases
Rocio Bruballa1, Carla Abuawad2, Luis Boccalatte3
1Hospital Italiano de Buenos Aires, Argentina. rocio.bruballa@hospitalitaliano.org.ar.
Abstract:
Squamous cell carcinoma of the tongue is the most common malignant tumor of the oral cavity. The finding of metastases, in this type of cancer, is considered the main factor of poor prognosis with a marked effect on the overall survival. The normal progression tends to be locoregional, at the surgical site or regional lymph nodes, and systemic involvement is usually uncommon. We present the case of a male patient, 40 years old, with tongue cancer and bilateral kidney metastases, eleven months after initial diagnosis. The aggressive biology, the extremely rare metastases location and a grim prognosis, illustrate an unusual case, which highlights the importance of its publication.
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