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Updated: Oct 31, 2025

Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of PhosphorusI
Published on: November 22, 2016
Design and Development of the First Peptide-Chelating Bisphosphane Bioconjugate from a Novel Functionalized
Hariprasad Gali1, Srinivasa R Karra1, V Sreenivasa Reddy1
1Department of Radiology, Center for Radiological Research, Allton Building Laboratories, Room 106, University of Missouri-Columbia, Columbia, MO 65211 (USA), Fax: (+1) 573-884-5679.
Abstract:
Remarkable oxidative stability is shown by the carboxylate-functionalized primary bisphosphane 1. Compound 1 can be used in conjugation reactions with biomolecules for functionalization through the COOH group without prior protection of PH2 groups. A novel water-soluble bisphosphane was obtained by reaction of the PH2 groups of 1 with formaldehyde under mild conditions.

