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Updated: Oct 31, 2025

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Control of membrane barrier during bacterial type-III protein secretion

Svenja Hüsing1,2, Manuel Halte1, Ulf van Look1,2

  • 1Institute for Biology-Bacterial Physiology, Humboldt-Universität zu Berlin, Berlin, Germany.

Nature Communications
|June 29, 2021
PubMed
Summary

Bacterial secretion systems use a methionine gasket (M-gasket) to rapidly export proteins while blocking small molecules. This M-gasket, along with other structures, maintains membrane integrity during high-speed protein transport.

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