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Updated: Oct 31, 2025

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
Published on: February 1, 2022
A reversible cause of left ventricular dysfunction: Case report and brief review
David Roque1, Daniel Faria1, João Ferreira1
1Serviço de Cardiologia, Hospital Professor Doutor Fernando da Fonseca, EPE, Amadora, Portugal.
Diabetic ketoacidosis can cause temporary left ventricular systolic dysfunction, impacting the cardiovascular system. Prompt diagnosis and management are crucial for recovery.
Area of Science:
- Cardiology
- Endocrinology
- Internal Medicine
Background:
- Diabetic ketoacidosis (DKA) is a serious complication of diabetes.
- Cardiovascular manifestations of DKA are not always apparent.
- Metabolic disorders can affect cardiac function.
Observation:
- A patient presented with DKA and elevated cardiac biomarkers (troponin I, natriuretic peptides).
- ECG showed repolarization abnormalities.
- Transthoracic echocardiogram revealed severe left ventricular systolic dysfunction.
Findings:
- DKA was identified as the likely cause of the cardiac dysfunction.
- Left ventricular function normalized within seven days.
- Profile L heart failure was diagnosed concurrently.
Implications:
- Metabolic and electrolyte disturbances, particularly DKA, should be considered in the differential diagnosis of new-onset heart failure.
- This case highlights a potential cardiovascular impact of diabetes.
- Early recognition of DKA-induced cardiomyopathy is essential for timely intervention.
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09:37Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
Published on: December 2, 2014
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