Related Experiment Video
Updated: Oct 31, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Severe recurrent pneumonia in children: Underlying causes and clinical profile in Vietnam
Kim Lam Hoang1, Anh Tuan Ta2, Van Thang Pham1
1Department of Pediatrics, Hanoi Medical University, Ton That Tung, Hanoi, Viet Nam.
Insights
Severe recurrent pneumonia in children often indicates underlying conditions. Identifying these causes is crucial for effective management in pediatric intensive care units.
Area of Science:
- Pediatric critical care medicine
- Respiratory medicine
- Infectious diseases
Background:
- Limited data exists on severe recurrent pneumonia (sRP) in children, particularly in developing nations like Vietnam.
- This study addresses the knowledge gap by investigating sRP in a Vietnamese pediatric intensive care unit (PICU).
Purpose of the Study:
- To identify the underlying causes of severe recurrent pneumonia in children admitted to the PICU.
- To describe the clinical profile of these pediatric patients.
Main Methods:
- A prospective, descriptive study was conducted.
- 110 children with severe pneumonia admitted to the PICU between November 2019 and August 2020 were analyzed.
- Data collection focused on clinical presentation and underlying diseases.
Main Results:
- Severe recurrent pneumonia constituted 29.4% of admissions.
- Underlying causes were identified in 91.8% of sRP cases, with respiratory, cardiovascular, and immune disorders being most frequent.
- Complications included prior intubation/ventilation (74.5%), shock (34.5%), and multiple organ failure (7.3%).
- Recurrent chest x-ray lesions in the same lobe were observed in 18.2% of cases.
Conclusions:
- The majority of children with severe recurrent pneumonia have an identifiable underlying disease.
- Comprehensive management strategies are essential for addressing sRP in pediatric populations.
Background:
There is still limited data on severe recurrent pneumonia in children, especially in developing countries as Vietnam. This study was conducted to identify the underlying causes and clinical profile of children with severe recurrent pneumonia admitted to the Pediatric Intensive Care Unit (PICU), National Children's Hospital.
Methods:
This was a prospective and descriptive study on 110 children with severe pneumonia admitted to the PICU from November 2019 to August 2020. Data were collected to investigate the clinical profile and underlying diseases.
Results:
Severe recurrent pneumonia accounted for 29.4%. Underlying causes were diagnosed in 91.8% of sRP children, in which the most common causes were abnormalities in respiratory, cardiovascular system and immune disorders. 74.5% of sRP children admitted to ICU had been previously intubated or ventilated, 34.5% had shock, 7.3% had multiple organ failure. Recurrent lesions on chest x-ray in the same lobe accounted for 18.2%.
Conclusions:
The majority of patients with severe recurrent pneumonia had an underlying disease. Comprehensive management is necessary for severe recurrent pneumonia.
More Related Videos
12:21A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
Published on: September 28, 2022
06:15Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Related Concept Videos
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia III: Complications and Assessment
Pneumonia II: Pathophysiology
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...