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Published on: November 6, 2019
Tonsillectomy Outcomes for Children With Severe Obesity
Susan Hines1,2, Kaci Pickett3, Kaitlyn Tholen4,5
1Breathing Institute, Children's Hospital Colorado, Aurora, Colorado, U.S.A.
Insights
Adenotonsillectomy (T&A) is effective for treating obstructive sleep apnea in severely obese children. After adjustments, children with Class 3 obesity have similar cure rates to Class 1, supporting T&A as a first-line treatment.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Obesity Research
Background:
- Severe obesity is increasingly prevalent in children.
- Obstructive sleep apnea (OSA) is a common comorbidity in obese children.
- The efficacy of adenotonsillectomy (T&A) for OSA in severely obese children requires further investigation using precise obesity metrics.
Purpose of the Study:
- To evaluate the success of T&A in treating pediatric severe obesity using an accurate obesity scale.
- To compare T&A outcomes across different classes of obesity in children aged 5-10 years.
Main Methods:
- A retrospective cohort study of children (5-10 years) with obesity who underwent T&A.
- Utilized data from Children's Hospital of Colorado (CHCO) and the Childhood Adenotonsillectomy Trial (CHAT).
- Classified obesity using body mass index (BMI) as a percentage of the 95th percentile (%BMIp95) into three classes.
Main Results:
- 132 patients analyzed: 53 (40%) Class 1, 45 (34%) Class 2, 34 (26%) Class 3 obesity.
- Overall OSA cure rate was 35.9%. Class 3 obesity had a lower initial cure rate (13%) compared to Class 1 (52%).
- After covariate adjustment, no significant difference in cure rates or key respiratory parameters (OAHI, oxygen saturation) was found between obesity classes.
Conclusions:
- T&A is an effective treatment for OSA in children across all obesity classes, including severe obesity (Class 3).
- Adjusting for covariates eliminates the observed disparity in cure rates between Class 1 and Class 3 obesity.
- Adenotonsillectomy should be considered a primary treatment option for children with obesity and OSA.
Objectives/Hypothesis:
To determine the success of an adenotonsillectomy (T&A) in treating children with severe obesity utilizing a more accurate obesity scale.
Study Design:
Retrospective cohort.
Methods:
A retrospective cohort of children with obesity between 5 and 10 years of age who underwent a T&A at Children's Hospital of Colorado (CHCO) was used. This study also utilized publicly available data from the Childhood Adenotonsillectomy Trial (CHAT) study. The cohort was divided into three obesity classes using age- and sex-specific body mass index (BMI) expressed as a percentage of the 95th percentile (%BMIp95) and compared for operative success differences.
Results:
There were 132 patients included in our primary analysis, with obesity distribution as follows: Class 1 to 53 patients (40%), Class 2 to 45 patients (34%), and Class 3 to 34 patients (26%). Overall, 52 patients (35.9%) experienced a cure (obstructive apnea/hypopnea index [OAHI] <1), with 27 (52%) patients in Class 1 obesity, 18 (35%) in Class 2, and 7 (13%) in Class 3. Class 3 had a significantly lower obstructive sleep apnea cure rate compared with Class 1 patients (P = .013), but after adjusting for covariates, this difference was no longer present (P > .05). There was no significant difference in the preoperative to postoperative percent change in mean oxygen saturation (P = .82 CHCO, P = .43 CHAT), oxygen nadir (P = .20 CHCO, P = .49 CHAT), or OAHI (P = .12 CHCO, P = .26 CHAT) between the obesity classes.
Conclusion:
After adjusting for covariates, children with Class 3 obesity are as likely to be cured with a T&A as those with Class 1 obesity. A T&A should be considered a first line treatment for all children with obesity.
Level Of Evidence:
3 Laryngoscope, 132:461-469, 2022.
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