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Updated: Oct 31, 2025

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

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Retraction

    Journal of Cellular Biochemistry
    |June 30, 2021
    PubMed

    Insights

    This study on microRNA-383-3p and IL1R2 has been retracted due to duplicated image elements in experimental data, invalidating its conclusions on endothelial injury.

    Area of Science:

    • Molecular Biology
    • Cardiovascular Research
    • Biochemistry

    Context:

    • Endothelial injury is a critical factor in cardiovascular diseases.
    • Homocysteine is implicated in endothelial dysfunction.
    • MicroRNAs play regulatory roles in cellular processes.

    Purpose:

    • To investigate the anti-inflammatory effect of microRNA-383-3p interacting with IL1R2.
    • To explore the mechanism against homocysteine-induced endothelial injury in rat coronary arteries.

    Summary:

    • The article investigated the interaction between microRNA-383-3p and IL1R2 in the context of homocysteine-induced endothelial injury.
    • Experimental data included image elements that were found to be duplicated in other scientific contexts.
    • The journal editors retracted the article due to concerns about the validity of the experimental data and conclusions.

    Impact:

    • The retraction highlights the importance of rigorous data verification in scientific publishing.
    • Invalidates previous findings on the role of microRNA-383-3p and IL1R2 in endothelial protection.
    • Underscores the need for careful review of image integrity in research articles.

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