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Updated: Oct 31, 2025

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

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Retraction

    Journal of Cellular Biochemistry
    |June 30, 2021
    PubMed

    Insights

    This study on gastric cancer development is retracted due to flawed data and inappropriate modifications in blot backgrounds. Original data could not be provided, invalidating the results.

    Area of Science:

    • Oncology
    • Molecular Biology
    • Biochemistry

    Context:

    • Gastric cancer is a significant global health concern.
    • Understanding the molecular mechanisms driving gastric cancer is crucial for developing effective therapies.

    Purpose:

    • To investigate the role of TCF12 in gastric cancer development.
    • To explore the regulatory relationship between miR-183 and TCF12.
    • To examine the involvement of the PI3K/AKT pathway in TCF12-mediated gastric cancer progression.

    Summary:

    • The article investigated the high expression of TCF12 in gastric cancer.
    • It proposed that TCF12 is regulated by miR-183 and activates the PI3K/AKT pathway.
    • However, the study was retracted due to flawed data, including inappropriate modifications in blot backgrounds.

    Impact:

    • The retraction highlights the importance of data integrity in scientific publishing.
    • It underscores the need for rigorous verification of experimental results, especially in cancer research.
    • This retraction prevents the dissemination of potentially misleading findings regarding gastric cancer pathogenesis.

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