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Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
Published on: September 20, 2021
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Disseminated Herpes Zoster During COVID-19
Olivier Voisin1, Nina Deluca1, Annabelle Mahé1
1Department of Internal Medicine.
Summary
This study reports the first documented case of recurrent herpes zoster (shingles) during a severe SARS-CoV-2 infection. The findings highlight potential viral interactions and dermatological manifestations during COVID-19 recovery.
Area of Science:
- Infectious Diseases
- Dermatology
- Virology
Background:
- The SARS-CoV-2 pandemic led to reports of various dermatological conditions, often attributed as secondary to the infection.
- Understanding the interplay between viral infections and dermatological manifestations is crucial for comprehensive patient care.
Observation:
- A patient hospitalized with severe SARS-CoV-2 infection experienced a recurrence of herpes zoster.
- The characteristic rash appeared on the 15th day of hospitalization during the patient's recovery phase.
Findings:
- Local swabs from the vesicles confirmed the presence of varicella-zoster virus, indicating a shingles reactivation.
- This case represents the first documented instance of herpes zoster recurrence in a patient with an active SARS-CoV-2 infection.
Implications:
- The findings suggest a potential link between SARS-CoV-2 infection and the reactivation of latent viruses like varicella-zoster.
- Further research is warranted to explore the immunological mechanisms underlying these dermatological comorbidities during COVID-19.
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