Related Experiment Video
Updated: Oct 31, 2025

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
Published on: January 7, 2019
Hydration of Hydrophilic Cloth Face Masks Enhances the Filtration of Nanoparticles
Christopher D Zangmeister1, James G Radney1, Matthew E Staymates1
1Material Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States.
Abstract:
Under high humidity conditions that mimic respiration, the filtration efficiency (FE) of hydrophilic fabrics increases when challenged with hygroscopic nanoparticles, for example, respiratory droplets containing SARS-CoV-2. The FE and differential pressure (ΔP) of natural, synthetic, and blended fabrics were measured as a function of relative humidity (RH) for particles with mobility diameters between 50 and 825 nm. Fabrics were equilibrated at 99% RH, mimicking conditions experienced when worn as a face mask. The FE increased after equilibration at 99% RH by a relative percentage of 33 ± 12% for fabrics composed of two layers of 100% cotton when challenged by 303 nm-mobility-diameter NaCl aerosol. The FE for samples of synthetics and polyester/cotton blends was unchanged upon equilibration at 99% RH. Increases in FE for 100% cotton fabrics were a function of particle size with a relative increase of 63% at the largest measured particle size (825 nm). The experimental results are consistent with increased particle capture due to H2O uptake and growth as the particles traverse the fabric.

