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Related Concept Videos

Radicals01:27

Radicals

77
Roots, often written as radicals, identify the quantity that must be raised to a specific exponent to produce a given value. A radical expression consists of two main components: the radicand, which is the value placed inside the root symbol, and the index, which indicates the degree of the root being taken. The notation n√a indicates the principal nth root of a. If n equals 2, the operation is the square root, while n = 3 defines the cube root. When n is even, a negative radicand does...
77
Radiation: Applications01:17

Radiation: Applications

1.3K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
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Radical Formation: Overview01:03

Radical Formation: Overview

2.3K
A bond can be broken either by heterolytic bond cleavage to form ions or homolytic bond cleavage to yield radicals. A fishhook arrow is used to represent the motion of a single electron in homolytic bond cleavage. There are two main sources from which radicals can be formed:
Radicals from spin-paired molecules:
Radicals can be obtained from spin-paired molecules either by homolysis or electron transfer. While two radicals are formed in the former, an electron is added in the...
2.3K
Radical Reactivity: Overview01:11

Radical Reactivity: Overview

2.3K
Radicals, the highly reactive species, gain stability by undergoing three different reactions. The first reaction involves a radical-radical coupling, in which a radical combines with another radical, forming a spin‐paired molecule. The second reaction is between a radical and a spin‐paired molecule, generating a new radical and a new spin‐paired molecule. The third reaction is radical decomposition in a unimolecular reaction, forming a new radical and a spin‐paired...
2.3K
Prismatic Beams: Problem Solving01:15

Prismatic Beams: Problem Solving

270
In the design of a supported timber beam subjected to a distributed load, both the beam's physical dimensions and the timber's characteristics, such as its grade and species, are critical. These factors determine the allowable stress values, which are crucial for calculating the necessary beam depth to ensure structural integrity and safety.
The design begins with analyzing the beam as a free body to identify moments and force balances, thereby determining support reactions. Next, the...
270
Radical Autoxidation01:20

Radical Autoxidation

2.6K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
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Updated: Oct 31, 2025

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The Role of CoLab and GAITS in Enabling the RADx Tech Program.

John M Collins1, Marshall R Collins1, Tamara McKenzie2

  • 1Center for the Integration of Medicine and Innovative Technology (CIMIT)Massachusetts General Hospital and Harvard Medical School Boston MA 02114 USA.

IEEE Open Journal of Engineering in Medicine and Biology
|June 30, 2021
PubMed
Summary
This summary is machine-generated.

The RADx Tech initiative rapidly developed innovative SARS-CoV-2 tests by mobilizing the biomedical community. A secure web infrastructure managed application selection and project commercialization, enabling swift return to daily activities.

Keywords:
CoLabGAITSRADx Techcommercializationhealthcare innovation

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Area of Science:

  • Biomedical Engineering
  • Public Health
  • Information Technology

Background:

  • The SARS-CoV-2 pandemic necessitated rapid development and deployment of diagnostic tests.
  • The RADx Tech initiative aimed to accelerate the creation and scaling of innovative testing solutions.
  • Effective management of diverse teams and complex workflows was critical for success.

Purpose of the Study:

  • To describe the secure, web-based infrastructure supporting the RADx Tech initiative.
  • To detail how the infrastructure addressed challenges in test development and commercialization.
  • To highlight the platforms used for application management and project acceleration.

Main Methods:

  • Development and configuration of a secure, web-based infrastructure.
  • Implementation of the CoLab platform for managing a multi-stage application selection process.
  • Utilization of the GAITS platform to support accelerated commercialization of selected projects.

Main Results:

  • The infrastructure enabled efficient and effective operation of key RADx Tech processes.
  • CoLab facilitated the management of a complex, interactive application selection workflow.
  • GAITS supported the progress of projects through an accelerated commercialization program.

Conclusions:

  • The described infrastructure was crucial for the RADx Tech initiative's success in rapidly deploying SARS-CoV-2 tests.
  • Secure and scalable web platforms are essential for managing large-scale, urgent biomedical research and development efforts.
  • The initiative's success demonstrates the potential of coordinated technological and community mobilization in public health crises.