Swept Source Optical Coherence Tomography Documenting Optic Nerve Involvement in an Aggressive T-Cell Lymphoma

Area of Science:

• Ophthalmology
• Hematology
• Medical Imaging

Background:

• Peripheral T-cell lymphomas (PTCLs) are aggressive hematological neoplasms.
• Ocular structure involvement in PTCLs is uncommon, often linked to CNS disease.
• Early detection and monitoring of ocular complications are crucial.

Observation:

• A case report detailing ocular findings in aggressive T-cell lymphoma.
• Utilized novel swept source optical coherence tomography (SS-OCT) for high-resolution imaging.
• SS-OCT offers enhanced speed, penetration, and field of view compared to conventional OCT.

Findings:

• SS-OCT identified significant ocular abnormalities in the patient.
• Documented increased retinal nerve fiber layer thickness.
• Observed prelaminar protrusion associated with the lymphoma, correlating with visual impairment.

Implications:

• SS-OCT may serve as a valuable tool for diagnosing and monitoring ocular manifestations of PTCLs.
• Understanding these findings can improve patient management and visual prognosis.
• Highlights the importance of considering ophthalmological evaluation in PTCL patients.