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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

741
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
560
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

250
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

285
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Palate Tuberculosis with Paradoxical Lymphadenitis.

Ines Kechaou1, Rym Abida1, Mohamed Salah Hamdi1

  • 1Department B of Internal Medicine, Faculty of Medicine, Charles Nicolle Hospital, University of Tunis El Manar, Tunis, Tunisia.

Journal of Global Infectious Diseases
|July 1, 2021
PubMed
Summary

Tuberculosis (TB) of the oral cavity is rare, but this case highlights a paradoxical reaction (PR) during treatment. Physicians should suspect TB in chronic oral lesions and consider PRs when lesions behave differently.

Keywords:
Oral ulcerspalatine tuberculosisparadoxical reaction

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Area of Science:

  • Infectious Diseases
  • Oral Medicine
  • Rheumatology

Background:

  • Oral tuberculosis, especially palatine involvement, is exceptionally rare, typically managed with standard antitubercular therapy.
  • Paradoxical reactions (PRs) can complicate tuberculosis treatment, posing diagnostic and management challenges for clinicians.

Observation:

  • A 30-year-old female with juvenile idiopathic arthritis and systemic lupus erythematosus presented with bifocal tuberculosis affecting the palate and cervical lymph nodes.
  • After two months of antitubercular therapy, the oral lesions showed favorable healing, while cervical lymph nodes exhibited a paradoxical reaction.

Findings:

  • The case demonstrates a rare instance of oral TB with a subsequent PR in cervical lymph nodes despite effective treatment of oral lesions.
  • This presentation underscores the complex and sometimes disparate responses to tuberculosis treatment.

Implications:

  • Clinicians should consider tuberculosis in cases of chronic, drug-resistant oral erosions.
  • Awareness of paradoxical reactions is crucial, especially when one TB lesion improves while another, like cervical lymphadenopathy, worsens during treatment.