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Updated: Oct 31, 2025

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Published on: August 12, 2018
Directions of Deep Brain Stimulation for Epilepsy and Parkinson's Disease
Ying-Chang Wu1, Ying-Siou Liao1, Wen-Hsiu Yeh2
1Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan, Taiwan.
Background:
Deep brain stimulation (DBS) is an effective treatment for movement disorders and neurological/psychiatric disorders. DBS has been approved for the control of Parkinson disease (PD) and epilepsy.
Objectives:
A systematic review and possible future direction of DBS system studies is performed in the open loop and closed-loop configuration on PD and epilepsy.
Methods:
We searched Google Scholar database for DBS system and development. DBS search results were categorized into clinical device and research system from the open-loop and closed-loop perspectives.
Results:
We performed literature review for DBS on PD and epilepsy in terms of system development by the open loop and closed-loop configuration. This study described development and trends for DBS in terms of electrode, recording, stimulation, and signal processing. The closed-loop DBS system raised a more attention in recent researches.
Conclusion:
We overviewed development and progress of DBS. Our results suggest that the closed-loop DBS is important for PD and epilepsy.
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