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Related Concept Videos

Tracheostomy: Procedure and Tubes01:28

Tracheostomy: Procedure and Tubes

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A tracheostomy is a surgical procedure that creates an artificial opening into the trachea, typically at the second or third cartilaginous ring level. This opening allows the insertion of a tracheostomy tube, which can replace an endotracheal tube, provide mechanical ventilation, bypass an upper airway obstruction, or remove accumulated tracheobronchial secretions.
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
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Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

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Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
197
Tracheostomy Care I: Pre-procedural Steps01:16

Tracheostomy Care I: Pre-procedural Steps

499
A tracheostomy is a surgical technique that involves making an incision in the neck to provide access to the trachea. It is frequently used in medical conditions such as airway obstruction and prolonged mechanical ventilation. Effective nursing management is crucial for the long-term success of a tracheostomy.
Required Equipment
The equipment necessary for tracheostomy care includes:
499
Trachea01:22

Trachea

3.1K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
3.1K
Oxygen Delivering System III: Tracheostomy and T-piece01:23

Oxygen Delivering System III: Tracheostomy and T-piece

3.1K
Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
3.1K
Tracheostomy Care II: Procedure01:25

Tracheostomy Care II: Procedure

595
Tracheostomy care is an essential nursing skill that involves cleaning and maintaining a tracheostomy tube to prevent infection and other complications. Here's a step-by-step guide explaining each procedure with its rationale. Note that disposable gloves are to be worn at all times and changed as often as needed to maintain a sterile work environment, and to protect both patient and healthcare worker.
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask...
595

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Related Experiment Video

Updated: Oct 30, 2025

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
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Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

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Current Strategies for Tracheal Replacement: A Review.

Giuseppe Damiano1, Vincenzo Davide Palumbo1,2, Salvatore Fazzotta1

  • 1Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy.

Life (Basel, Switzerland)
|July 2, 2021
PubMed
Summary

Researchers are exploring regenerative medicine for tracheal replacement, focusing on bio-prosthesis and decellularized tissue scaffolds. Challenges include ensuring vascular supply and biocompatible adhesion to prevent rejection and maintain mechanical integrity for improved quality of life.

Keywords:
biocompatible materialsbioengineeringscaffoldssurgical biotechnologies

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Manufacture of a Multi-Purpose Low-Cost Animal Bench-Model for Teaching Tracheostomy
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Manufacture of a Multi-Purpose Low-Cost Animal Bench-Model for Teaching Tracheostomy

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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Related Experiment Videos

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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

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Area of Science:

  • Regenerative medicine
  • Biomaterials science
  • Transplantation immunology

Background:

  • Increasing incidence of airway cancers necessitates effective tracheal replacement strategies.
  • Tracheal resection, while common, leads to significant post-operative complications impacting quality of life.
  • Current research focuses on bio-prosthesis and tissue engineering for tracheal reconstruction.

Purpose of the Study:

  • To review current research and past attempts in tracheal replacement using regenerative medicine.
  • To highlight the potential of decellularized biological scaffolds for tracheal transplantation.
  • To discuss challenges and advancements in achieving successful tracheal regeneration and transplantation.

Main Methods:

  • Review of existing literature on tracheal replacement techniques and bio-prosthesis development.
  • Analysis of decellularized tissue scaffolds derived from native extracellular matrix.
  • Investigation into methods for promoting vascularization and cell differentiation on scaffolds.
  • Evaluation of adhesion strategies using biocompatible glues and substrate integration.

Main Results:

  • Decellularized biological scaffolds offer a promising 3D structure supporting perfusion and vascularization.
  • Modulating experimental parameters can alter scaffold surface characteristics for improved cell integration.
  • Challenges remain in achieving robust adhesion and avoiding immunogenic responses and rejection.

Conclusions:

  • Regenerative medicine approaches, particularly using decellularized scaffolds, show potential for tracheal replacement.
  • Ensuring effective vascular supply, biocompatible adhesion, and immunological compatibility are critical for success.
  • Further research is needed to overcome current limitations and advance tracheal transplantation.