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Ion Pairs for Transdermal and Dermal Drug Delivery: A Review

Mignon Cristofoli1, Chin-Ping Kung2, Jonathan Hadgraft2

  • 1School of Human Sciences, London Metropolitan University, 166-220 Holloway Road, London N7 8DB, UK.

Pharmaceutics
|July 2, 2021
PubMed
Summary

Ion pairing enhances topical drug delivery by forming neutral complexes that improve skin permeation. This strategy can also control or prevent drug penetration and stabilize formulations, offering versatile applications in drug delivery.

Keywords:
counter ionshumanion pairpartitionpermeationporcineskintopical

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