Related Experiment Video

Updated: Oct 30, 2025

Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing
08:19

Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing

Published on: July 7, 2020

10.9K

Colistin Resistance in Aeromonas spp

Luis Uriel Gonzalez-Avila1, Miguel Angel Loyola-Cruz1,2, Cecilia Hernández-Cortez3

  • 1Laboratorio de Investigación Clínica y Ambiental, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Carpio y Plan de Ayala, Col. Casco de Santo Tomás, Ciudad de México 11340, Mexico.

International Journal of Molecular Sciences
|July 2, 2021
PubMed

Insights

Colistin resistance in Aeromonas bacteria is increasing due to antimicrobial use. This resistance, linked to mcr genes, is found in clinical, animal, and environmental Aeromonas strains.

Area of Science:

  • Microbiology
  • Antimicrobial Resistance
  • One Health

Background:

  • Increased antimicrobial use, including colistin, drives the emergence of resistant bacteria.
  • Aeromonas species are increasingly identified with resistance to colistin, a critical last-resort antibiotic.
  • Colistin resistance mechanisms, particularly mcr genes, are detected across various environments and hosts.

Purpose of the Study:

  • To provide an overview of colistin resistance in Aeromonas.
  • To discuss the properties of colistin as an antimicrobial agent.
  • To review methods for detecting colistin resistance in Aeromonas.

Main Methods:

  • Literature review on colistin resistance in Aeromonas.
  • Analysis of studies reporting mcr gene variants (mcr-1, mcr-3, mcr-5) in Aeromonas.
  • Discussion of phenotypic and genotypic methods for colistin resistance determination.

Main Results:

  • Aeromonas strains exhibiting colistin resistance have been identified in clinical, animal, and environmental samples.
  • Detection of mcr-1, mcr-3, and mcr-5 gene variants in Aeromonas isolates.
  • Various methods exist for determining colistin resistance, with specific considerations for Aeromonas.

Conclusions:

  • Colistin resistance in Aeromonas is a growing concern across human, animal, and environmental health sectors.
  • Understanding resistance mechanisms and detection methods is crucial for surveillance and control.
  • Further research is needed to monitor the spread and impact of colistin-resistant Aeromonas.
Keywords:
Aeromonasantimicrobial resistancecolistin

More Related Videos

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

7.0K
Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung09:26

Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung

Published on: January 22, 2021

7.3K

Related Concept Videos

Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
673
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
174
Antibiotic Selection00:57

Antibiotic Selection

Overview
56.8K
Antimicrobial Proteins01:23

Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
11.2K