Related Experiment Video
Updated: Oct 30, 2025

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets
Published on: May 11, 2015
Pulmonary Hypertension: Diagnosis and Management
1Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Center for Postgraduate Medical Education, ECZ-Otwock, 05-400 Otwock, Poland.
This special issue focuses on diagnosing and treating pulmonary hypertension (PH). It covers the latest advancements and clinical insights for managing this complex cardiovascular condition.
Area of Science:
- Cardiology
- Pulmonology
- Medical Diagnostics
Background:
- Pulmonary Hypertension (PH) is a severe condition impacting lung vasculature.
- Accurate diagnosis and timely treatment are crucial for patient outcomes.
- This special issue addresses current challenges in PH management.
Discussion:
- Explores novel diagnostic tools and biomarkers for early PH detection.
- Reviews current therapeutic strategies, including pharmacological and non-pharmacological interventions.
- Discusses the importance of a multidisciplinary approach in PH care.
Key Insights:
- Highlights recent breakthroughs in understanding PH pathophysiology.
- Emphasizes the need for personalized treatment algorithms based on PH subtype.
- Showcases advancements in imaging and hemodynamic assessment.
Outlook:
- Predicts future trends in PH research and clinical practice.
- Addresses unmet needs in PH treatment and patient monitoring.
- Encourages further investigation into rare forms of pulmonary hypertension.
Related Concept Videos
Pulmonary Hypertension: Classification and Pathogenesis
There are various classifications for PH, each relating to different underlying causes and also...
Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

