Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Design Consideration01:22

Design Consideration

382
Designing a structure involves a series of considerations, primarily the material's ultimate strength, calculated through tests that measure changes under increased force until the material reaches its breaking point or limit. The ultimate load, where the material breaks, is divided by its original cross-sectional area, resulting in the ultimate normal stress or strength. The ultimate shearing stress is another significant factor taken into account.
The factor of safety is another key...
382
Design Example: Analyzing Capacity Contours for Flood Risk Assessment01:17

Design Example: Analyzing Capacity Contours for Flood Risk Assessment

162
Flood risk assessment involves careful planning and analysis to ensure the safety of communities near water retention structures. Capacity contours are a vital tool in this process, as they illustrate the potential spread of water at specific levels in a given area. In the context of building a bund across a small valley, these contours play a critical role in evaluating the safety of nearby residential areas.In this example, the bund is intended to store stormwater in the valley. The engineers...
162
Design Example: Calculating Safe Diameter for Wind-Exposed Disc01:17

Design Example: Calculating Safe Diameter for Wind-Exposed Disc

213
Assessing safety in wind-exposed installations is crucial to preventing potential failures. This example explores the calculation and design adjustments needed to mount a circular disc on a building facade, where wind forces are a primary concern. A 4-meter diameter disc was initially designed as an aesthetic feature facing winds at a velocity of 25 meters per second, with an air density of 1.25 kilograms per cubic meter. Given these conditions, the drag force on the disc was determined using...
213
Design Example: Creating a Hydraulic Model of a Dam Spillway01:21

Design Example: Creating a Hydraulic Model of a Dam Spillway

429
Scaled hydraulic models of dam spillways provide a practical way to replicate and study the intricate flow dynamics of these structures. Often built to a 1:15 ratio, these models allow for observing critical water behavior, such as velocity distribution, flow patterns, and energy dissipation.
429
Indeterminate Structure01:18

Indeterminate Structure

1.1K
Indeterminate structures refer to structures where internal forces and reactions cannot be determined using only the equations of static equilibrium.  Indeterminate structures have more unknown forces and reaction forces than equations of static equilibrium that can be used to determine them. Indeterminate structures are often used in engineering to create complex, efficient, and aesthetically pleasing structures. There are various types of indeterminate structures used in engineering and...
1.1K
Design of Prismatic Beams for Bending01:23

Design of Prismatic Beams for Bending

449
The design of prismatic beams, structural elements with a uniform cross-section, focuses on ensuring safety and structural integrity under load. The design process begins by determining the allowable stress, either from material properties tables, or by dividing the material's ultimate strength by a safety factor. This safety factor is essential for accommodating uncertainties, and varies depending on the material—timber, steel, or concrete—with each having unique strength and...
449

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multigram-Scale Asymmetric Alkene Reduction Catalyzed by a Thermostable Flavin Ene-Reductase.

Organic process research & development·2026
Same author

Digitalisation and automation in smart biomanufacturing: uncertainties, challenges and early pathways towards safe and sustainable design.

New biotechnology·2026
Same author

Elevating Haloperoxidase Expression in Escherichia coli through Fusion with a Formate Oxidase.

Chembiochem : a European journal of chemical biology·2026
Same author

Principles, Materials, and Devices for Solar-to-Chemical Biotransformation.

Chemical reviews·2026
Same author

Surface engineering and functionalization of powder-based materials by fluidized-bed atomic layer deposition for emerging applications.

RSC advances·2026
Same author

Stereocontrolled Synthesis of α-Branched Tetrahydropyrans by a One-Pot-Two-Step Photobiocatalytic Cascade of Citronellol.

Journal of natural products·2026
Same journal

Correction: Grewal et al. Diversity and Representation in Cardiovascular Research: Evidence Gaps, Emerging Models, and Policy Implications. <i>Int. J. Environ. Res. Public Health</i> 2026, <i>23</i>, 241.

International journal of environmental research and public health·2026
Same journal

Drinking Water Quality and Health Risk Assessment in Rural Ghana: Evidence from North-East and North Gonja Districts in the Savannah Region.

International journal of environmental research and public health·2026
Same journal

Physical Activity of University Students During COVID-19 Restrictions: Evidence from Poland.

International journal of environmental research and public health·2026
Same journal

Assessment of Occupational Health and Safety Hazards in Mosquito Control Personnel in North Carolina and Virginia, USA.

International journal of environmental research and public health·2026
Same journal

Association Between Dysfunctional Parenting Practices and Suspected Gaming Disorder Among Japanese Male Junior High School Students: A Cross-Sectional Study of Parental Assessment.

International journal of environmental research and public health·2026
Same journal

A National Virtual Peer Support Group for Women Veterans Living with Breast Cancer: Lessons from the Field.

International journal of environmental research and public health·2026
See all related articles

Related Experiment Video

Updated: Oct 30, 2025

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
09:05

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

121

Safe-by-Design in Engineering: An Overview and Comparative Analysis of Engineering Disciplines.

Pieter van Gelder1, Pim Klaassen2, Behnam Taebi1

  • 1Safety and Security Institute, Delft University of Technology, 2600 GA Delft, The Netherlands.

International Journal of Environmental Research and Public Health
|July 2, 2021
PubMed
Summary
This summary is machine-generated.

Safe-by-Design principles are explored across diverse engineering fields, revealing commonalities and differences in safety strategies. This approach integrates social sciences to proactively embed safety into technological innovation.

Keywords:
design for valuesresponsible research and innovationrisk-based designsafe-by-designsecure-by-designuncertainty

More Related Videos

Micro-scale Engineering for Cell Biology
04:42

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

5.0K
A Modeling and Simulation Method for Preliminary Design of an Electro-Variable Displacement Pump
09:04

A Modeling and Simulation Method for Preliminary Design of an Electro-Variable Displacement Pump

Published on: June 1, 2022

3.3K

Related Experiment Videos

Last Updated: Oct 30, 2025

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
09:05

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

121
Micro-scale Engineering for Cell Biology
04:42

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

5.0K
A Modeling and Simulation Method for Preliminary Design of an Electro-Variable Displacement Pump
09:04

A Modeling and Simulation Method for Preliminary Design of an Electro-Variable Displacement Pump

Published on: June 1, 2022

3.3K

Area of Science:

  • Engineering
  • Risk Management
  • Sociotechnical Systems

Background:

  • Safe-by-Design (SbD) is a proactive approach to integrating safety considerations throughout the engineering design process.
  • Numerous engineering disciplines have developed unique practices for hazard identification, risk assessment, and safety management.
  • Cross-disciplinary analysis is crucial for identifying shared challenges and fostering mutual learning in safety engineering.

Purpose of the Study:

  • To provide a comprehensive overview of Safe-by-Design (SbD) implementation across various engineering disciplines.
  • To identify commonalities, differences, and opportunities for cross-disciplinary learning in safety practices.
  • To position SbD as an integral component of Responsible Research and Innovation (RRI).

Main Methods:

  • Comparative analysis of SbD practices in eight engineering disciplines: construction, chemical, aerospace, urban, software, bio, nano, and cyber space engineering.
  • Examination of technology, hazards, social challenges, risk management strategies, design principles, and tools within each discipline.
  • Investigation of empirical data on design strategies to identify interdisciplinary commonalities and differences.

Main Results:

  • Significant variations exist in how SbD is applied across disciplines, influenced by historical development and specific technological hazards.
  • Common themes include risk management strategies, safety-promoting design principles, and the use of specific methods and tools.
  • Safe-by-Design is effectively an elaboration of Responsible Research and Innovation (RRI), balancing safety with other values like sustainability and equity.

Conclusions:

  • Safe-by-Design facilitates collaboration between social sciences/humanities and engineering to proactively incorporate safety.
  • It serves as a practical tool for policymakers and risk assessors in developing governance for safety.
  • SbD helps navigate technological development by balancing optimism with precaution, acknowledging inherent uncertainties.