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Analytical Treatment Interruption in HIV Trials: Statistical and Study Design Considerations

Lu Zheng1, Camlin Tierney2, Ronald J Bosch2

  • 1Center for Biostatistics in AIDS Research, Department of Biostatistics, Harvard T.H. Chan School of Public Health, 651 Huntington Avenue, Boston, MA, 02115, USA. szheng@sdac.harvard.edu.

Current HIV/AIDS Reports
|July 2, 2021
PubMed
Summary

Analytical treatment interruption (ATI) trials are crucial for HIV remission research. Study designs now feature shorter interruptions and frequent monitoring to minimize viral rebound risks.

Keywords:
Analytical treatment interruptionAntiretroviral therapyClinical trialsHIV remissionHIV reservoirHistorical control

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