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Related Experiment Video

Updated: Oct 30, 2025

Isolation of Murine Lymph Node Stromal Cells

Isolation of Murine Lymph Node Stromal Cells

Published on: August 19, 2014

Micronodular Thymoma with Lymphoid Stroma: A Case Report.

Takehiro Tsuchiya¹, Atsushi Sano, Mitsuaki Kawashima

¹Department of Thoracic Surgery, Chigasaki Municipal Hospital, Honson 5-15-1, Chigasaki, Kanagawa 253-0042, Japan. tatsuchiya-ths@umin.ac.jp.

The Tokai Journal of Experimental and Clinical Medicine

|July 3, 2021

Summary

Micronodular thymoma with lymphoid stroma (MNT) is a rare thymic neoplasm. Complete surgical resection of MNT offers a good prognosis, with no reported recurrences or deaths.

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Last Updated: Oct 30, 2025

Isolation of Murine Lymph Node Stromal Cells

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Published on: August 19, 2014

Spontaneous Murine Model of Anaplastic Thyroid Cancer

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Published on: February 3, 2023

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

Published on: August 9, 2019

Area of Science:

Oncology
Pathology

Background:

Micronodular thymoma with lymphoid stroma (MNT) is a rare thymic neoplasm.
Established clinical guidelines, diagnostic criteria, prognostic factors, and therapeutic regimens are lacking for MNT.

Observation:

A 69-year-old woman presented with an anterior mediastinal mass.
Imaging revealed a 65×28×15 mm tumor.
Histopathology showed micronodules with abundant lymphocytes and lymphoid follicles, positive for CAM, CK5/6, and TdT.

Findings:

The patient underwent successful thymectomy for MNT, staged as WHO Class I.
The patient remained recurrence-free for seven years post-surgery.
MNT exhibits a favorable prognosis when completely resected, with no reported instances of recurrence, metastasis, or tumor-related mortality.

Implications:

MNT is considered a borderline tumor with an excellent prognosis.
Preoperative diagnosis of MNT is challenging.
Complete surgical resection is recommended for suspected mediastinal masses to ensure accurate diagnosis and long-term survival.