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Related Experiment Video

Updated: Oct 30, 2025

Sleeve Gastrectomy in Mice using Surgical Clips
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Perinatal outcomes after bariatric surgery.

Darios Getahun1, Michael J Fassett2, Steven J Jacobsen3

  • 1Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA; Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA.

American Journal of Obstetrics and Gynecology
|July 3, 2021
PubMed
Summary

Bariatric surgery significantly reduces risks for gestational diabetes, preeclampsia, and cesarean delivery in pregnant women. However, it increases the risk of delivering small for gestational age neonates, requiring close monitoring.

Keywords:
bariatric surgeryobesityperinatal outcomesweight retention

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Area of Science:

  • Obstetrics and Gynecology
  • Bariatric Surgery Outcomes
  • Maternal-Fetal Medicine

Background:

  • Bariatric surgery is a key treatment for obesity, offering long-term weight management and health improvements.
  • Pregnancy post-bariatric surgery is increasing, yet population-based data on perinatal outcomes remain limited.

Purpose of the Study:

  • To investigate the association between bariatric surgery and adverse perinatal outcomes.
  • To determine if factors like postsurgery weight, gestational weight gain, surgery type, timing, or maternal comorbidities modify these risks.

Main Methods:

  • Retrospective cohort study using the Bariatric Surgery Registry and electronic health records.
  • Included 20,213 women who delivered at ≥20 weeks gestation after bariatric surgery.
  • Utilized ICD codes and logistic regression with inverse probability of treatment weighting for analysis.

Main Results:

  • Bariatric surgery was linked to reduced risks of gestational diabetes, preeclampsia, chorioamnionitis, cesarean delivery, large for gestational age neonates, macrosomia, and NICU admission.
  • A significantly increased risk for small for gestational age neonates was observed (aOR, 2.46).
  • These risks were independent of the time interval between surgery and pregnancy.

Conclusions:

  • Bariatric surgery offers significant pregnancy outcome benefits for women with severe obesity.
  • Close monitoring is crucial for women with prior bariatric surgery to mitigate risks of small for gestational age neonates and postpartum hemorrhage.