Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantifying the Impact of Headlamp Light Distribution on Automotive Camera Perception: Establishing a New Primary Design Parameter.

Sensors (Basel, Switzerland)·2026
Same author

Toward adaptation-aware optimization of tunable multi-LED lighting: modeling illuminance-dependent hue-bin preference targets.

Optics express·2026
Same author

When Does Directional Reflectance Matter? Evaluating BRDF Effects in Plant Canopy Light Simulations.

Plants (Basel, Switzerland)·2026
Same author

Guided Endodontic Management of Pulp Canal Obliteration in a Maxillary Canine with Root Resorption and Prior Iatrogenic Deviation: A Case Report.

Iranian endodontic journal·2025
Same author

Comparative Efficacy of Digital Flexible Ureteroscopy in Management of Renal Stones in Normal-Weight and Overweight/Obese Patients.

Research and reports in urology·2025
Same author

Incorporating Spectral and Directional Leaf Reflectance into Virtual Plant Models via Phong Shader Parameter Fitting.

Plants (Basel, Switzerland)·2025
Same journal

CEST MRI reveals nicotine-induced alterations in glutamate-associated molecular connectivity in the mouse brain.

Frontiers in neuroscience·2026
Same journal

Brain protein burden is related to intravoxel incoherent motion: PET-MR imaging study.

Frontiers in neuroscience·2026
Same journal

Screening the optimal rTSMS frequency to orchestrate immune-fibrotic remodeling for adult spinal cord repair.

Frontiers in neuroscience·2026
Same journal

Assessment of tenecteplase target-associated pathogenic mechanisms underlying depression in acute ischemic stroke patients: insights from artificial intelligence-driven multi-omics analysis and <i>in vitro</i> validation.

Frontiers in neuroscience·2026
Same journal

Sex-divergent intrinsic brain function in Parkinson's disease: elevated nigral fluctuations and premotor-visuospatial coupling in female patients.

Frontiers in neuroscience·2026
Same journal

Spatial transcriptomics on an expanded dataset at the brain-electrode interface: exploration of variability and identification of novel biomarkers.

Frontiers in neuroscience·2026
See all related articles

Related Experiment Video

Updated: Oct 30, 2025

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
08:27

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Published on: March 3, 2023

1.2K

PupilEXT: Flexible Open-Source Platform for High-Resolution Pupillometry in Vision Research.

Babak Zandi1, Moritz Lode1, Alexander Herzog1

  • 1Laboratory of Lighting Technology, Department of Electrical Engineering and Information Technology, Technical University of Darmstadt, Darmstadt, Germany.

Frontiers in Neuroscience
|July 5, 2021
PubMed
Summary
This summary is machine-generated.

This study introduces PupilEXT, an open-source pupillometry platform for precise pupil measurement. It offers professional-grade remote eye-tracking software and hardware, making cognitive research more accessible.

Keywords:
eye trackingopen sourcepupil diameterpupil measurementpupillometrystereo cameravision research

More Related Videos

VisualEyes: A Modular Software System for Oculomotor Experimentation
10:41

VisualEyes: A Modular Software System for Oculomotor Experimentation

Published on: March 25, 2011

12.9K
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.5K

Related Experiment Videos

Last Updated: Oct 30, 2025

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
08:27

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Published on: March 3, 2023

1.2K
VisualEyes: A Modular Software System for Oculomotor Experimentation
10:41

VisualEyes: A Modular Software System for Oculomotor Experimentation

Published on: March 25, 2011

12.9K
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.5K

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Biomedical Engineering

Background:

  • The human pupil's response is a key biomarker for cognitive processes, driven by intrinsically photosensitive retinal ganglion cells.
  • Accurate measurement of subtle pupil diameter changes (10-2 mm) is crucial for detecting neurocognitive effects.
  • Existing commercial pupillometry systems are expensive and use proprietary software, limiting research accessibility and algorithm transparency.

Purpose of the Study:

  • To develop an open-source, cost-effective pupillometry platform for professional remote pupil measurement in laboratory settings.
  • To provide a user-friendly, cross-platform software solution (PupilEXT) for pupil response research.
  • To integrate and evaluate state-of-the-art open-source pupil detection algorithms.

Main Methods:

  • Development of an integrated hardware and software pupillometry platform, PupilEXT, compatible with macOS, Windows, and Linux.
  • Implementation of six advanced open-source pupil detection algorithms: Starburst, Swirski, ExCuSe, ElSe, PuRe, and PuReST.
  • Creation of a 120-fps demo system for calibration and accuracy assessment in stereo mode.

Main Results:

  • The developed system achieved a calibration accuracy of 0.003 mm and an average temporal pupil measurement detection accuracy of 0.0059 mm in stereo mode.
  • PupilEXT software offers comprehensive features including advanced pupil detection, measurement validation, data acquisition, and stereo vision capabilities.
  • The platform is system-independent and provides a user-friendly graphical interface for professional pupil response research.

Conclusions:

  • The open-source PupilEXT platform provides a professional, accessible, and accurate alternative to high-cost commercial pupillometry systems.
  • This accessible tool democratizes advanced pupil measurement for cognitive neuroscience and related research fields.
  • The platform's open-source nature fosters transparency and further development in pupillometry algorithms and applications.