Related Experiment Video
Updated: Oct 30, 2025
An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma
Published on: November 15, 2024
Prolonged survival after laser interstitial thermal therapy in glioblastoma
A Basit Khan1, Carlos Kamiya Matsuoka2, Sungho Lee1
1Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, United States.
Background:
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Management includes surgical resection followed by chemoradiation, and prognosis remains poor. Surgical resection is not possible for some deep-seated or eloquent tumors. Laser interstitial thermal therapy (LITT) has emerged as a new, minimally invasive surgical option for deep-seated GBM.
Case Description:
We report a case of newly diagnosed thalamic GBM managed with LITT followed by radiation and chemotherapy.
Conclusion:
The patient remains well at 50-month post-LITT, indicating a potentially unique durability of LITT treatment in GBM.
