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Published on: January 12, 2018
Maternal predictive factors for preterm birth: A case-control study in Southern Iran
Azin Alavi1, Parisa Razmjoue2, Ali Safari-Moradabadi3
1Fertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Insights
Maternal factors like cervical insufficiency, placenta previa, and previous preterm birth significantly increase the risk of preterm birth (PTB). Early identification and management of these conditions are crucial for reducing PTB rates.
Area of Science:
- Obstetrics and Gynecology
- Perinatology
- Public Health
Background:
- Preterm birth (PTB) is a leading cause of infant mortality and chronic disease.
- Identifying maternal risk factors is crucial for preventing PTB and improving infant outcomes.
Purpose of the Study:
- To determine maternal factors associated with preterm infant birth in Bandar Abbas.
- To provide data for targeted interventions to reduce PTB rates.
Main Methods:
- A case-control study involving 400 preterm infants.
- Data collected through maternal interviews and medical records.
- Conditional logistic regression used to analyze risk factors.
Main Results:
- Significant risk factors for PTB included type of delivery, preeclampsia, history of PTB, premature rupture of membranes, placental abruption, placenta previa, and cervical insufficiency.
- Prenatal care was found to be a protective factor (OR = 0.334).
- Cervical insufficiency (OR = 11) and placenta previa (OR = 9.333) were strongly associated with PTB.
Conclusions:
- Cervical insufficiency, history of placenta previa, and history of preterm birth are key risk factors for PTB.
- Early recognition and management of these conditions can help reduce PTB.
- Targeted prenatal care strategies are essential for high-risk pregnancies.
Background:
Preterm birth (PTB) is one of the most important factors that increase the risk of chronic diseases and postpartum death in infants. The aim of this study was to determine the maternal factors that affect the birth of preterm infants in the city of Bandar Abbas.
Materials And Methods:
This is a case-control study that was performed on 400 preterm infants. Sampling was done by a simple method, and information was gathered by interviewing the mothers and their medical records. Data were collected by SPSS software version 16. To compare risk factors in the two groups, conditional logistic regression was used, and P < 0.05 was considered statistically significant.
Results:
Results showed that factors such as type of delivery (odds ratio [OR] = 3.584, 95% confidence interval [CI]: 1.981-6.485), preeclampsia (OR = 2.688, 95% CI: 1.164-6.207), history of PTB (OR = 4.171, 95% CI: 1.483-11.728), premature rupture of membranes (OR = 3.273, 95% CI: 1.745-6.137), care during prenatal (OR = 0.334, 95% CI: 0.159-0.701), placental abruption (OR = 3.209, 95% CI: 1.209-8.519), placenta previa (OR = 9.333, 95% CI: 2.086-41.770), and cervical insufficiency (OR = 11, 95% CI: 1.381-87.641) were independent risk factors of preterm infant birth.
Conclusions:
The PTB risk is higher for women with cervical insufficiency, history of placenta previa, and history of preterm. Early recognition and management of these high-risk conditions among pregnant women may lead to a reduction in PTB rates.
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