Related Experiment Video
Updated: Oct 30, 2025

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
Contact dermatitis: An important consideration in leg ulcers
Afsaneh Alavi1, Alina Goldenberg2, Sharon Jacob3
1Division of Dermatology, University of Toronto, Toronto, Ontario, Canada.
Abstract:
The prevalence of chronic wounds is increasing with the aging population, with 1% to 2% of the worldwide population experiencing leg ulcers and positive patch tests reported in up to 75% of this population. With the introduction of modern dressings and compression therapies, clinicians should be cognizant of the potential risk of contact dermatitis in patients with leg ulcers. Contact dermatitis (both allergic and irritant) to wound products may present as maceration, pain, and overall impaired wound healing. Herein, we review the literature on contact dermatitis to wound-care products.
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